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J Transl Med 2017;15:111

This inherent heterogeneity underscores the necessity of adopting personalized approaches to understanding and targeting mitochondrial abnormalities in different cell types and tissues

Branches of the hepatic artery and portal vein are seen in the portal triads along with bile ducts and are separated from the hepatic cords by a limiting plate of hepatocytes

Notably, this function is mediated not by its canonical role in promoting degradation, but through a novel mechanism involving non-degradative ubiquitination that modulates KCNN3 activity